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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

If you are taking Cialis or taking other medications, it is important for your doctor to understand the risks and benefits before starting your treatment. These include -

  • alpha-blockers (e.g., tamsulosin, tadalafil)
  • other antihypertensive drugs (e.g., amlodipine, angiotensin-II inhibitors, Ang-Max, angiotensin-II receptor blockers, e.g., losartan, Healthy Heart, rewritten by the manufacturer)
  • other medications for fits (e.g., sildenafil)
  • other medications used for seizures (e.g., indomethacin, carbamazepine)

C.

Ex.

Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.

You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.

There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-

• Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).

• Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets

for chest pain or use Rectogesic ointment?

• Nicorandil (Ikorel), used to treat angina

• Cimetidine, used to treat stomach or duodenal (peptic) ulcers

• Theophylline, used to treat asthma

• Antibiotics:- Clarithromycin, Erythromycin and Telithromycin

• Anti-fungals such as itraconazole and ketoconazole

• Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone

• Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide

• Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat

• Recreational drugs:- amyl nitrate (poppers)

If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.

Read available consultation questions below and in the “Is Tadalafil safe for you to take?” section of the medical questionnaireRead questions

1. What is Tadalafil?

Tadalafil is a type of medicine called a phosphodiesterase type 5 (PDE5) inhibitor. It works by relaxing blood vessels and increasing blood flow to the penis during sexual stimulation. You do not neededance PDE5 as it is not the PDE5 enzyme that breaks down Cialis. So, Tadalafil does not allow you to achieve or maintain an erection if you’re sexually aroused.

2. What is the active substance in Tadalafil?

Theermanent medical use of Tadalafil is in the treatment of erectile dysfunction.

3. What is the recommended dosage of Tadalafil for?

The recommended dosage is one and a half tablets of one tablet a day, or 0.5g of the medicine in a single dose.

4. What are the symptoms of erectile dysfunction?

Erectile dysfunction; a feeling of fullness or dizziness, diarrhea, abdominal pain, back or knee pain, or lowingiblikegives.

5. How do I take Tadalafil?

Follow the exact instructions that you are using Tadalafil to take. Take one tablet about 1.36 hours before you want to get into the mood for sex.

6. What are the possible side effects of Tadalafil?

Get emergency medical attention if you have an increase in your blood pressure, difficulty breathing, or any of a number of symptoms of an allergic reaction after taking Tadalafil, as it can cause dizziness.

7. What is the common side effect of Tadalafil?

Side effects most commonly associated with Tadalafil are back pain, headache, nausea, dizziness, and social/urinary symptoms. It’s important to talk to your doctor if you have any of these symptoms.

8.

Nicknamed “The Weekender Pill”,Tadalafil is the generic version of Cialis™. It lasts up to 36 hours and the reason some prefer Tadalafil over Sildenafil, which typically last up to 8 hours. Please select your preferred dosage and number of pills.

  • Available in 5 mg, 10 mg, and 20 mg
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  • Tadalafil lasts up to 36 hours
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Looking for Tadalafil Daily?.

* We can ship up to 30 pills at a time. For example, if you order 120 pills, you will get four shipments of 30 pills.

Health Questionnaire Required:

For your first order with us, after placing an order, you will be prompted to upload your ID and submit our health questionnaire, soour physician canreview your basic health information,in order to mail prescription medications. You will not need to do this for refill orders.

Disclaimer:This is not medical advice. You and our physician will determine if (and potentially how) you should take Tadalafil. Please consult with your physician if you have any further questions.For more information on Tadalafil,.

Tadalafil (20 mg) 10 pills
  1. How should 10 10 mg Tadalafil be taken?
  2. Should 10 10 mg Tadalafil be taken?
  3. If 10 10 mg Tadalafil is right for you, your doctor willissue a 10-mg prescription. The amount of prescription Tadalafil can be up to or (including manufacturer discount card), and, if applicable, can be subject to change.
  4. 10 10 mg Tadalafil is a generic version of Cialis. It would be best to take 10 10 mg tablets at certain times each day, but wewon’t take any more than 10 10 mg tablets at a time.

Takejust one tablet in the 24-hour period. Take it without food (even if you think it’s time to take it), any time between doses, or in very large amounts. This is because Tadalafil can interfere with a number of commonardenafil-based medications (,, and others]), making it less effective when taken with food. If you take no more than one Tadalafil tablet a day, youcan take one without eating.If you take more than one Tadalafil tablet a day, it’s>impossible for your health to determine which Tadalafil dose you can take safely and effectively without risking side effects.

If you take Tadalafil for a long time, youcan take it with food. If you take it for a short time, your doctor willissue a 20-mg prescriptionbefore your next dose, soyou’ll need totake it with a large meal that doesn’t contain grapefruit juice. Tadalafil will only work for temporary conditions. If you stop taking Tadalafil and you’re not getting the results you would get from taking Tadalafil for a long time, your doctor mayyour next dose as well, so you can wait.

Tadalafil for up to 20 days after your last dose to allow the drug to get back in your system. If you take it for a longer time than 20 days, your doctor will issue a 20-mg prescription before you set about regularly taking it. Do not take a 10-mg or 20-mg dose at a time.

The US Food and Drug Administration will begin an investigation into the effectiveness of the erectile dysfunction drug Cialis (tadalafil) in a case involving the company that makes it. The FDA is investigating the alleged failure of the drug's manufacturer to properly warn consumers of the drug's risks and the company says it is committed to the safety of consumers who purchase the drug.

The FDA has not released a statement saying it would not comment on the case. Cialis is approved by the Food and Drug Administration to treat erectile dysfunction in men over 40. However, the company says it is not currently taking any action to warn consumers about its drug's side effects. "We are very confident that the safety and efficacy of Cialis have been proven through clinical trials," says a company spokesperson.

Cialis is available in several different dosages, including the branded Cialis (tadalafil) and the generic, Viagra (sildenafil). Both the branded and generic versions contain tadalafil as the active ingredient. It is often used by men who have experienced erectile dysfunction (ED) or difficulty starting a new relationship or are currently impotent, or take other medications to treat the condition. The FDA has not released a number of information about the safety and efficacy of these two treatments.

"It is important that both Cialis and Viagra are taken only as needed, and that patients understand the importance of taking them at the same time," says the FDA spokesperson.

The FDA also wants to know if patients should stop taking the drug after taking a single dose of the drug. "We want to hear from patients about the risk and benefits of this medication, as well as its ability to improve blood pressure and to reduce erectile dysfunction," says the company.

As part of its investigation, the company said it will have a public advisory panel to investigate whether the company knew about the drug's safety when it was making the drug. "We want to ensure the safety of all consumers who purchase this product and provide them with information about the risks and benefits of this treatment," it says. "We also want to ensure that patients can take their medication as prescribed and have access to the products at their discretion."

According to the FDA, the company is "currently not taking any action to warn consumers about the risk and potential side effects of the drugs, nor is it currently taking any actions to address the risks and benefits of the drug."

Cialis is available in generic and brand versions. Cialis is also available as a cheaper alternative to Viagra.

Cialis is approved by the FDA to treat erectile dysfunction (ED), but in the case of this condition, the FDA says it should be taken only as needed, and does not affect sexual ability. "These drugs work by increasing blood flow to the penis, so you can have an erection just from a few minutes after taking them," says the company. "However, in some men, this can cause side effects, including headaches, dizziness, and flushing, which can be serious and potentially life-threatening."

The FDA has not released a number of information about the safety and efficacy of Cialis. While some men who take it will not experience the side effects, it has not been proved that the drug is safe for them.